Not giving up anything physical, mind you; the physical body would simply be a sensory input device and a tool to manipulate the physical environment. (Perhaps one of many -- why limit yourself to just one body at a time? Not to mention various other sorts of physical interaction choices one might have - virus sized, or wide area sensor nets, you could take direct input from a telescope [shared or personal], the choices are limitless.)
Once one is primarily a digital entity, there would basically be no concept of death like what we have today. Artists could continue creating art forever -- imagine if Da Vinci was still alive and working actively the past 500 years; this could be true of whoever goes digital. Imagine the depths of philosophical thought that could be achieved with near infinite time to spend on it, the depths of science if scientists could keep on working with ever stable and even increasing mental vigor instead of declining.
I realize this might not appeal to everyone, but sign me up.
